Stem cells are the core of regenerative medicine. Adult stem cells are a kind of stem cells existing in adult individuals, which have the potential of self-renewal and differentiation. Therefore, when it is used for the treatment of a damaging disease, the corresponding tissue can be regenerated, the tissue damage can be repaired, and the tissue function can be restored. The isolation and expansion of adult stem cells is a prerequisite for their application.Scientists have developed various techniques for isolation and expansion of adult stem cells in vitro, which can extract and expan high quality stem cells from different types of tissues (lung, kidney, uterus, liver, kidney, prostate, gastrointestinal tract and pancreas), and gradually establish an industrial production system of adult stem cells in accordance with GMP specifications to produce corresponding cell preparation products to provide strong support for clinical application of regenerative medicine.

The lungs are important organs of the human body. In the process of performing respiratory tasks, it is unavoidable to be exposed to external or internal harmful substances (such as air pollution, tobacco, bacterial viruses or toxic substances in blood), which often lead to large-scale damage of lung tissue, thus leading to acute and chronic lung injury diseases (such as respiratory distress syndrome ARDS, chronic obstructive pulmonary disease COPD, interstitial lung disease ILD and bronchiectasis BE, etc.). At present, there is no effective way to reverse the progress of these diseases. Regend’s scientists are working on innovative research in the fields of lung stem cells, lung organ development, and lung micro-organs, aiming at repairing lung injury caused by lung injury disease, restoring lung function, and exploring new means for the treatment of lung injury disease. At the same time, we are also committed to the development of "super lungs" with antibacterial ability, combined with tissue engineering technology to carry out research on artificial lungs, broadening the application of lung stem cells. At present, some research results have been published in many internationally renowned academic journals such as Nature and Protein and Cell.

Liver disease has a high mortality rate worldwide, but it also causes serious public health problems. Liver transplantation is the last resort for the treatment of end-stage liver diseases. However, due to organ shortage, post-operative complications, immune rejection and other factors, there is an urgent need for new methods for the treatment of liver diseases. Regend's scientists are committed to the study of stem cell-specific hepatic precursor cells in the liver, and at the same time explore their use in liver regeneration, to solve various problems faced in the application process, to provide strong support for the use of hepatic precursor cells in the treatment of liver diseases, so that the "liver regeneration" of Pulmatius in Greek mythology becomes a reality.

Partial tracheectomy is often caused by tumors, physical and chemical factors. After that, some tissue engineering products are needed to reconstruct the trachea. At present, medical macromolecule materials are mostly used to form reticular tubules. Although they have excellent biocompatibility and stable structural characteristics, they can match the adjacent tissues and withstand pressure from surrounding tissues, problems such as incomplete epithelialization of the lumen and granulation formation in the tracheal cavity need to be solved urgently. To solve these problems, Regend scientists are committed to innovative research that combines airway adult stem cells with existing artificial trachea, so that regenerative medicine technology and tissue engineering technology can be organically integrated to solve major problems in the field of artificial trachea, and further promote the application of artificial trachea.