Blue: Functional lung volume
Red: Emphysema volume
Yellow: Infiltration volume
我们的研究成果已在多家国际权威同行评审期刊上发表，充分体现了我们致力于推动干细胞与人体器官再生医学发展的决心。
欢迎查阅下方已发表的论文，进一步了解我们的技术与临床创新。
如果您对我们的研究成果有任何疑问，或希望获取更多信息，欢迎随时联系我们。
PRE-CLINICAL
Control of airway basal stem cell–mediated lung repair by TGF-β signaling
Tingting Zou, Shiyu Zhang, Mingzhe Liu, Qiaoyu Chen, Siyu Wang, Lingyun Niu, Ye-Guang Chen, Ting Zhang, Wei Zuo
Science Advances | January 7, 2026
PRE-CLINICAL
Cloned airway basal progenitor cells to repair fibrotic lung through re-epithelialization
Yu Zhao, Yueqing Zhou, Weipan Zhang, Mingzhe Liu, Jun Duan, Xiaopeng Zhang, Qiwang Ma, Yujia Wang, Yuzhen Zhang, Zhongliang Guo, Ting Zhang & Wei Zuo
Nature Communications | February 03, 2025
CLINICAL
Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial
Shiyu Zhang, Min Zhou, chi Shao, Yu Zhao, Mingzhe Liu, Lei Ni, Zhiyao Bao, Qiurui Zhang, Ting Zhang, Qun Luo , jieming Qu , Zuojun
Xu , Wei Zuo
eLife | December 13, 2024
CLINICAL
Autologous transplantation of P63+ lung progenitor cells in patients with bronchiectasis: A randomized, single-blind, controlled trial
Jiayang Yan, Weipan Zhang, Yun Feng, Xuefei Liu, Lingyun Niu, Yi Guo, Ling Zhou, Mengmeng Shi, Caixia Di, Qiurui Zhang, Xiaofei Wang, Jianping Zhou, Ranran Dai, Lei Ni, Zhiyao Bao, Tianli Yan, Yun Hu, Ping Wang, Ting Zhang, Min Zhou, Wei Zuo, Jieming Qu
Cell Reports Medicine | November 19, 2024
CLINICAL
Autologous transplantation of P63+ lung progenitor cells for chronic obstructive pulmonary disease therapy
Yujia Wang, Zili Meng, Ming Liu, Yueqing Zhou, Difei Chen, Yu Zhao, Ting Zhang, Nanshan Zhong, Xiaotian Dai, Shiyue Li, Wei Zuo
Science Translational Medicine | February 14, 2024
DOI: https://www.science.org/doi/10.1126/scitranslmed.adi3360
PRE-CLINICAL
Generation of renal tubular organoids from adult SOX9+ kidney progenitor cells
Dewei Zhou, Dandan Li, Hao Nie, Jun Duan, Sarah Liu, Yujia Wang, Wei Zuo
Life Medicine | November 22, 2023
NON-CLINICAL
Urinary single-cell sequence analysis of the urinary macrophage in different outcomes of membranous nephropathy
Xi Liu, Yu Zhao, Yangyang Niu, Qionghong Xie, Hao Nie, Yun Jin, Yingying Zhang, Yuqiu Lu, Saiya Zhu, Wei Zuo, Chen Yu
Clinical Kidney Journal | June 05，2023
NON-CLINICAL
Single-cell transcriptome profiling of the vaginal epithelium reveals the heterogeneity of suprabasal cells
Chen Liang, Zixian Zhao, Sarah Liu, Ting Zhang, Wei Zuo
Precision Clinical Medicine | March 20, 2023
PRE-CLINICAL
WT1+ glomerular parietal epithelial progenitors promote renal proximal tubule regeneration after severe acute kidney injury
Xizhen Hong, Hao Nie, Juan Deng, Shiting Liang, Liting Chen, Jing Li, Siqiao Gong, Guobao Wang, Wei Zuo, Fanfan Hou, Fujian Zhang
Theranostics | February 21, 2023
PRE-CLINICAL
Activated SOX9+ renal epithelial cells promote kidney repair through secreting factors
Hao Nie, Zixian Zhao, Dewei Zhou, Dandan Li, Yujia Wang, Yu Ma, Xutao Liu, Wei Zuo
Cell Proliferation | December 21, 2022
NON-CLINICAL
The Effect of Strict Lockdown on Omicron SARS-CoV-2 Variant Transmission in Shanghai
Haibo Yang, Hao Nie, Dewei Zhou, Yujia Wang, Wei Zuo
Vaccines | August 25, 2022
NON-CLINICAL
Single-cell analysis defines the lineage plasticity of stem cells in cervix epithelium
Zixian Zhao, Yujia Wang, Yingchuan Wu, Dandan Li, Ting Zhang, Yu Ma, Xiaoming Teng, Wei Zuo
Cell Regeneration | November 01, 2021
PRE-CLINICAL
Stable Long-Term Culture of Human Distal Airway Stem Cells for Transplantation
Yueqing Zhou, Yujia Wang, Dandan Li, Ting Zhang, Yu Ma, Wei Zuo
Stem Cells International | September 17, 2021
PRE-CLINICAL
Intrapulmonary distal airway stem cell transplantation repairs lung injury in chronic obstructive pulmonary disease
Xiaofan Wang, Yu Zhao, Dandan Li, Yun Feng, Yusang Xie, Yueqing Zhou, Min Zhou, Yujia Wang, Jieming Qu, Wei Zuo
Cell Proliferation | April 9, 2021
PRE-CLINICAL
Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine
Yujia Wang, Yu Zhao, Zixian Zhao, Dandan Li, Hao Nie, Yufen Sun, Xiaobei Feng, Ting Zhang, Yu Ma, Jing Nie, Guangyan Cai, Xiangmei Chen, Wei Zuo
Protein& Cell | January 09, 2021
NON-CLINICAL
Single-cell analysis identified lung progenitor cells in COVID-19 patients
Zixian Zhao, Yu Zhao, Yueqing Zhou, Xiaofan Wang, Ting Zhang, Wei Zuo
Cell Proliferation | October 3, 2020
NON-CLINICAL
Single-Cell RNA Expression Profiling of ACE2, the Receptor of SARS-CoV-2
Yu Zhao, Zixian Zhao, Yujia Wang, Yueqing Zhou, Yu Ma, Wei Zuo
American Journal of Respiratory and Critical Care Medicine | September 1 2020
PRE-CLINICAL
Genetically engineered distal airway stem cell transplantation protects mice from pulmonary infection
Yue-qing Zhou, Yun Shi, Ling Yang, Yu-fen Sun, Yu-fei Han, Zi-xian Zhao, Yu-jia Wang, Ying Liu, Yu Ma, Ting Zhang, Tao Ren, Tina P Dale, Nicholas R Forsyth, Fa-guang Jin, Jie-ming Qu, Wei Zuo & Jin-fu Xu
EMBO Molecular Medicine | November 29, 2019
DOI: https://link.springer.com/article/10.15252/emmm.201810233
PRE-CLINICAL
Distal airway stem cells ameliorate bleomycin-induced pulmonary fibrosis in mice
Yun Shi, Mingqing Dong, Yueqing Zhou, Wangping Li, Yongheng Gao, Luyao Han, Min Chen, Hongwei Lin, Wei Zuo, Faguang Jin
Stem Cell Research & Therapy | June 03, 2019
PRE-CLINICAL
Regeneration of functional alveoli by adult human SOX9+airway basal cell transplantation
Qiwang Ma, Yu Ma, Xiaotian Dai, Tao Ren, Yingjie Fu, Wenbin Liu, Yufei Han, Yingchuan Wu, Yu Cheng, Ting Zhang, Wei Zuo
Protein& Cell | January 17, 2018
PRE-CLINICAL
p63+Krt5+ distal airway stem cells are essential for lung regeneration
Wei Zuo, Ting Zhang, Daniel Zheng'An Wu, Shou Ping Guan, Audrey-Ann Liew, Yusuke Yamamoto, Xia Wang, Siew Joo Lim, Matthew Vincent, Mark Lessard, Christopher P Crum, Wa Xian, Frank McKeon
Nature | November 12, 2014